You might be wondering which drug you can use to cure low sexual arousal. Don’t worry though, there is something that can help you. Enter PT-141, by another name Bremelanotide. PT-141 is a synthetic peptide that is created from melanotan 2; a generic version of this medicine.
So if you or someone is suffering from ED (Erectile dysfunction) then Bremelanotide is the best option for you. This medicine can be used by both women and men for treating erectile dysfunction.
This medicine differs from other medicines that are used in treating the same problem. For this reason, don’t use it as you would other medications.
Besides curing HSDD( hypoactive sexual desire disorder) PT-141 works in your body to offer you more health benefits.
Before we look at the benefits of using PT-141(bremelanotide), there are several aspects of this medicine that we need to examine first.
Let’s dive right in!
What is PT 141?
By another name Bremelanotide, PT-141 is a synthetic peptide made from MT-II (Melanotan 2). This generic term refers to a new synthetic pharmaceutical-grade aphrodisiac peptide.
This peptide was originally made to act as a tanning agent. It’s also an MSH (melanocyte-stimulating hormone) that will affect your sexual arousal, thus helps enhance your libido levels and even penile erections.
Unlike Cialis or Viagra, PT-141 isn’t a PDES inhibitor. Also, it doesn’t target your vascular system. But instead, it targets your nervous system by activating the neurons in your hypothalamus to enhance your sexual desire.
What makes PT-141 different from Viagra and other medications?
Note that Viagra and other similar sex supplements target the vascular system. However, PT-141 works directly on your hypothalamus to enhance your desire. This is why Levitra, Viagra, and other medications are not aphrodisiacs because they don’t directly affect your libido.
Using PDE5 and PT-141 inhibitors do offer synergistic effects. Although PT141 was initially tried as a sunless tanning agent, this product has displayed unexpected side effects of unprompted sexual arousal and erections.
During PT-141clinical trials it showed to be helpful as a treatment for erectile dysfunction in both males and females.
PT-141, a cyclic analog heptapeptide lactam of alpha-MSH, that activates your central nervous system’s melanocortin receptors MC4-R and MC3-R.
Bremelanotide or PT-14, a research peptide that Is presently being tested for its impacts on sexual dysfunction. A metabolite of MT-2 or Melanotan 2, ( a tanning peptide), that does not have the C group Terminal amide. PT 141 peptide contains 2 or more chains of amino acids that are linked by amide bonds. Note that amide bonds are called peptide bonds.
The PT141 is the chain of amino acid with the chemical formula C50H68N14O10 with the structural Name: cyclo-[Nle4, Asp5, D-Phe7, Lys10]alpha-MSH-(4-10)
With the molar mass of 1025.2 g/mol
PT-141 was discovered as an agent for sexual activity enhancement by accident. An all credit goes to a scientist known as Mac Hadley who generously volunteered himself. Since he was conducting the experiments on his body, Mac Hadley ended up having an eight-hour erection due to a double dose of the earlier compound, Melanotan II, during his earliest testing.
The first α-MSH testing was carried out in the 1960s on rats and then continued into the 80s. The peptide hormones Melanocortins are responsible for regulating numerous physiological functions.
The Melanocortin analog called Melanotan I was initially tested for tanning, and Melanotan II as an agent for sexual dysfunction agent.
Often used as a solution to treat erectile dysfunction.
Most men choose to use Bremelanotide in re-igniting their passion as it helps them engage in sexual activity and attain extremely hard erections. This effect not only helps satisfy them but even their partners during physical intercourse.
When you are using the PT-141 peptide, you don’t need to use other therapies or medications such as hormone replacement therapy to get the best results.
What science says…
Studies have proven the ability of PT141 for treating sexual dysfunction through performing experiments on lab rats. The male lab rats used as subjects in these experiments had erectile dysfunction and PT-141 was used.
After use, there was an improvement in the sexual performance as compared to their control group that did not receive this peptide.
Other than the male rats getting such benefits, PT-141 was also used on female rats and showed significant improvements by displaying an increase in their sexual performance as well.
When it comes to humans, we can say that the potential positive effects of sexually active life are guaranteed when using PT-141.
Therefore, if you are seeking a comprehensive therapy to help improve your sexual desire as well as improve your sex life, Bremelanotide may just be what you need.
This is the perfect alternative instead of opting for several other medications or therapies for treating sexual dysfunctions in women or men.
Functioning Of PT-141
When it comes to scientific studies, the PT-141 peptide has proven its worth by helping solve sexual problems in both women and men through increasing their desire for sexual intercourse as well as improving their sexual performance. The reason behind this is since this peptide helps stimulate mPOA (medial preoptic area) terminals in your brain.
This action helped researchers identify PT141 as a stimulator which can activate your brain’s dopamine hormones. Dopamine plays a key function in motivating sexual function among humans.
Also, Dopamine is the compound known to act as a neurotransmitter which stimulates performance. If your levels of dopamine are low in your brain, it then means your libido is also low.
Therefore, you are likely to show less attention to your sexual desire and even sexual activities. Compared to other people with sufficient levels of dopamine, it’s been proven that the latter tend to show more interest in their sexual desire and even gets aroused easily than people with lower dopamine levels.
Reviews have even shown that Bremelanotide can treat low libido problems successfully. Because of this, this peptide has become popular thanks to the benefit it provides.
More than a treatment for sexual dysfunction
What’s more, this is an effective treatment for addressing sexual dysfunctions like erectile dysfunction and it’s extremely pocket-friendly. So, if you are on a budget, you can still choose to use this peptide treatment for treating low libido.
The latest passion when it comes to this peptide therapy is that couples are even using PT-141 together for them to get optimal benefits in improving their sexual activities as well as overall sex lives.
Most of its users are impressed by this PT-141 treatment thanks to its ability to boost their sexual desires as well as in the effects this treatment has on their overall sexual performances.
Today, its users are sharing raving reviews online on how this peptide played a key role in restoring their love life.
That said, one thing you should keep in mind is that the effects and benefits of using Bremelanotide treatment will vary from one individual to the next. Realize that these results can be affected by factors like your body’s reactions and functions.
Advantages of using PT141
Treats the inability to engage in sexual intercourse
PT141 offers this basic and most popular advantage for people who suffer from HSDD (hypoactive sexual desire disorder). It works through stimulating your brain into producing the required hormones and even signal for heightening your sexual desire instead of increasing your blood flow throughout the body.
Acts as a healing agent
Although this drug is still going through research and development, it has shown that it could be used as an healing-agent too for various injuries.
More research is ongoing to determine the possibilities of this drug playing a more effective role in bodybuilding and muscle healing. What’s more, there is a possibility that Bremelanotide may be used by athletes as a replacement for many expensive peptides.
Researchers are trying to make PT 141 as a drug that will, in future, serve as a multipurpose peptide. Recently, researchers discovered the reason behind making it a multipurpose drug thanks to its effects as a healing agent.
Also, the studies have observed the potential of PT141 to ACT as a heart disease cure. Based on this, we could say that PT141 can be offered as a multipurpose medication for different disorders and diseases.
How Can I Benefit from Bremelanotide?
Bremelanotide can offer you a variety of benefits. Besides treating disorders with skin pigmentation, it can even be used for tanning. Thus, it makes it possible for you to get that natural tan without having exposure to direct sunlight. Since PT 141 tends to lead to sexual arousal, it’s not a component for commercial tanning products.
Injecting PT-141 can be beneficial for you in the below-mentioned ways:
- Increases sexual desire and sex drive
- Increased your sexual frequency
- Acts as a treatment for impotence and erectile dysfunction
- Treats HSDD (Hypoactive Sexual Desire Disorders)
- Boosts your natural energy levels
- Relieves tiredness or lethargy
By using PT-141, its immediate effects aren’t the only advantages you might see. By this we mean, with enhanced sexual activity can help improve your physical and mental well-being.
Also, it can help improve your immune system. In women, it can promote bladder control as well as strengthen the pelvic floor muscles.
And in men, it will lower the risk of a heart attack or stroke (based on The American Journal of Cardiology). Additional benefits are related to those observed with exercising, including burning calories and fats, lowering blood pressure, as well as reducing stress levels.
To get the best results, you must maintain the quality of your peptide. Meaning it should thus be kept under refrigeration until use. Also, keep your vial closed until its time to use. Also, PT 141 should be reconstituted before you can inject it.
Effects of PT 141 in Men?
In men, PT 141 can effectively treat sexual dysfunction – that is premature ejaculation, impotence and erectile dysfunction.
During the first testing, Melanotan II induces tanning but in addition, it caused unexpected side effects of sexual arousal as well as spontaneous erections in 9 out of 10 male test subjects.
PT- 141 has even shown to have important results in male test subjects, with what was described as “frequent” and “intense” erections that would last between 2 to 6 hours.
Effects of PT 141 in Women?
New studies indicate that more than 43% of women in the US experience little to no sexual satisfaction from orgasms and only 25 per cent achieve orgasm from intercourse. Luckily, there are many libido treatments for those women who want to experience greater sexual fulfilment, more intimacy and improved relationships.
Nonetheless, more women have reported moderate to high sexual desire after using bremelanotide treatment versus placebo.
For women who engaged in sexual activity within 24 hours after their treatment, it was noted that significantly many were satisfied with the level of their sexual arousal when on bremelanotide, compared to those using the placebo.
Bremelanotide For Bodybuilding
PT-141 peptide has been subjected to lots of experiments and it’s still undergoing further research and clinical studies. And especially to determine its potency in bodybuilding. So far researchers and scientists have discovered the ability of PT-141 to help in healing injuries and shock resulting from hemorrhages.
However, there’s still more to study in this area. Even then, it’s clear from this healing property of PT-141 can benefit many bodybuilders and persons engaged in daily rigorous physical activities.
By using this peptide, recovery of muscle exertions and post-workout will be improved. No factual report of using Bremelanotide alone for post-workout recovery has surfaced, however, if you use PT-141 for enhancing your sex life while undertaking strenuous physical activities, then you can enjoy the additional benefits of PT-141 peptide.
Hopefully, further research will be undertaken on the benefits of using this peptide for bodybuilding or in professional sports. More so as many more studies generate discoveries linked to the positive benefits of this peptide.
Which form does PT141 come in?
The only legal form of this peptide is injectable, which is available as vial which is around 10 mg. When you use the light dose of this medicine, you should then take about 20 mg with a 10 mg dose of the vial.
If you are looking for an effective option, then you should go for PT-141 that is injected like insulin. Avoid using the nasal and oral form since they will not offer you useful results.
But always check with your doctor before using this peptide.
How to use PT-141?
Before getting PT141 and any other peptide, make sure to consult your health care professional or doctor to ascertain that you are a candidate before beginning your treatment.
Bremelanotide is injected subcutaneously. It was earlier available in different forms but was discontinued since it led to increased cases of blood pressure in the test subjects.
In the recent past, it’s been redeveloped in an injection form, to help treat different sexual dysfunctions in both females and male.
Typically, subcutaneous injections are applied in areas where you have fat deposits in your body. Some points you can inject include your stomach area, lower abdomen or the thigh.
Remember to administer the vial at the same time every day for best results. Creams, nasal sprays, pills, and other forms of the PT 141 peptide, outside the injection vials, aren’t legitimate forms of PT141.
Does it Involve Any Reconstituting?
When using PT141, you’ll need to reconstitute the solution. It’s recommended that you use bacteriostatic water. Also, you can use sterile water. When mixing the vial and bac water, use a syringe.
Withdraw 1 cc or one full ml of the bac water then inject it into the PT-141. Always point the needle towards the glass, for it to trickle down and doesn’t damage the peptide.
The swirl it to mix (never shake the bottle) the vial for the peptide to fully dissolve.
The reconstituted PT-141 peptide using bac water will preserve for 6-12 months. When you use sterile water, the Pt-141 vial will last for 1 month before degrading.
Typically, Bremelanotide is applied to the subcutaneous skin layer in the human body. As an alternative, nasal atomizers are opted for by most users.
But before you start using this drug, it is important that you read and also understand the directions given on the PT-141 peptide label. Doing so will offer you optimal results in a protected and safe manner.
Also, PT-141 is available in powder form that should be reconstituted using bacteriostatic water to allow for easy administering.
Facts to note on the dosage of PT-141:
- You should use a dose of between 0.5 to 2 mg at a time.
- PT-141 should be used within 2 to 4 hours before you engage in sexual intercourse.
- If you decide to stack several PT-141s, it’s recommended that you mix the contents in a single syringe to help reduce the total number of injections.
- You should administer this peptide subcutaneously; it’s best to opt for the area around the abdomen for injecting this peptide. Then using an insulin syringe you can inject the peptide.
- It’s best that you practice effective self-injection and also disposal methods. This way you do not have to depend too much on others while undergoing this peptide treatment.
- If you are new to this task, we recommend that you get help from an experienced medical practitioner so that you can learn how to best self-inject. All you will need to do is consider this peptide treatment when you are seeking to get back your libido and overcome sexual dysfunctions.
- Remember that you avoid increasing your dosage without the advice or recommendation from your physician. This is even though there are no words of caution that have been raised as regards an overdose.
- Above all, you will need to be patient while undertaking your peptide treatment to get positive results as concerns your sexual problems as well as low libido levels.
PT 141 Side Effects
Bremelanotide usage can have some side effects, like flushing, headaches, and nausea, which were observed in the trials these side effects vary in intensity levels that range between mild and moderate.
Also, it can cause itchiness, pain on the injected areas and infection on the upper respiratory tract.
What’s the Current Status of PT-141?
In June 2018, AMAG Pharmaceuticals announced that F.D.A. had accepted their application for a review on bremelanotide (PT141) as a new medication.
After the anticipated completion of its reviewing in March 2019, In June 2019, FDA approved,Bremelanotide injection as a treatment for HSDD in premenopausal women.
How to store PT 141?
For you to use PT 141, it first must be reconstituted, which means it should be kept under refrigeration. Therefore, you may want to store the vial tightly closed until you are ready to administer it.
PT-141 appears to be among the most promising peptides which can provide you with the best results when it concerns improving your sexual life for women and offering harder, longer-lasting erections for men. The PT-141 peptide is highly recommended for all people. Meaning both women and men, who feel like they are not getting the most from their lives. This is since they cannot actively indulge in sexual intercourse because of physical inhibitions.
PT141 works naturally to activate parts of your human body that are dormant due to inefficiency and/or sexual dysfunctions. Why not make the most of this opportunity to get this great solution for addressing your sexual problems and turn your love life around?
Before starting your peptide therapy, be sure that you consult your health practitioner to confirm that you are a candidate for this treatment. When using this peptide, only increase your dose under a doctor’s supervision.
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Luke is ProvHosp’s in-house journalist interested in all things natural. A graduate of the University of Michigan’s Journalism program, Luke is always eager to get the next story of discovery in the field of health sciences.